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USP43 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q70EL4 |
| Other Accession | NP_694942.3 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 122809 Da |
| Antigen Region | 900-928 aa |
| Gene ID | 124739 |
|---|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase 43, Deubiquitinating enzyme 43, Ubiquitin thioesterase 43, Ubiquitin-specific-processing protease 43, USP43 |
| Target/Specificity | This USP43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 900-928 amino acids from the C-terminal region of human USP43. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | USP43 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | USP43 |
|---|---|
| Function | May recognize and hydrolyze the peptide bond at the C- terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins (By similarity). |
| Tissue Location | Expressed in brain, aorta and lung at low levels. |
Provided below are standard protocols that you may find useful for product applications.
Background
USP43 may recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins (By similarity).
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Quesada, V., et al. Biochem. Biophys. Res. Commun. 314(1):54-62(2004) Puente, X.S., et al. Nat. Rev. Genet. 4(7):544-558(2003)
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