|Application ||WB, E|
|Calculated MW||48065 Da|
|Antigen Region||76-104 aa|
|Other Names||MAPK/MAK/MRK overlapping kinase, MOK protein kinase, Serine/threonine kinase 30, Mok, Rage, Stk30|
|Target/Specificity||This Mouse Rage antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the N-terminal region of mouse Rage.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Rage Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Able to phosphorylate several exogenous substrates and to undergo autophosphorylation (PubMed:10421840). Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner (PubMed:25243405).|
|Cellular Location||Cytoplasm. Cell projection, cilium. Nucleus|
|Tissue Location||Highly expressed in testis, and less in kidney, brain and lung|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Rage is able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
Sun, L., et al. Cardiovasc. Res. 82(2):371-381(2009)
Zeng, S., et al. J. Hepatol. 50(5):929-936(2009)
Bjork, P., et al. PLoS Biol. 7 (4), E97 (2009) :
Aneja, R.K., et al. J. Leukoc. Biol. 84(5):1326-1334(2008)
Chen, Y., et al. J. Immunol. 181(6):4272-4278(2008)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.