|Application ||WB, E|
|Calculated MW||48065 Da|
|Antigen Region||76-104 aa|
|Other Names||MAPK/MAK/MRK overlapping kinase, MOK protein kinase, Serine/threonine kinase 30, Mok, Rage, Stk30|
|Target/Specificity||This Mouse Rage antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the N-terminal region of mouse Rage.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Rage Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Able to phosphorylate several exogenous substrates and to undergo autophosphorylation (PubMed:10421840). Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner (PubMed:25243405).|
|Cellular Location||Cytoplasm. Cell projection, cilium. Nucleus|
|Tissue Location||Highly expressed in testis, and less in kidney, brain and lung|
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Provided below are standard protocols that you may find useful for product applications.
Rage is able to phosphorylate several exogenous substrates and to undergo autophosphorylation.
Sun, L., et al. Cardiovasc. Res. 82(2):371-381(2009)
Zeng, S., et al. J. Hepatol. 50(5):929-936(2009)
Bjork, P., et al. PLoS Biol. 7 (4), E97 (2009) :
Aneja, R.K., et al. J. Leukoc. Biol. 84(5):1326-1334(2008)
Chen, Y., et al. J. Immunol. 181(6):4272-4278(2008)
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