|Application ||WB, IHC-P, E|
|Other Accession||Q63430, Q91YQ3, NP_055275.1|
|Calculated MW||16786 Da|
|Antigen Region||76-105 aa|
|Other Names||Cold shock domain-containing protein C2, RNA-binding protein PIPPin, CSDC2, PIPPIN|
|Target/Specificity||This PIPPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human PIPPIN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PIPPIN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Note=PIPPin-RNA complexes are located to the nucleus.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Schafer, C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4), G726-G734 (2003) :
Raimondi, L., et al. J. Cell. Mol. Med. 7(1):35-42(2003)
Nastasi, T., et al. Neuroreport 11(10):2233-2236(2000)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.