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PIPPIN Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - PIPPIN Antibody (Center) AP14318C
    PIPPIN Antibody (Center) (Cat. #AP14318c) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PIPPIN antibody detected the PIPPIN protein (arrow).
  • IHC-P - PIPPIN Antibody (Center) AP14318C
    PIPPIN Antibody (Center) (Cat. #AP14318c)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PIPPIN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9Y534
Other Accession Q63430, Q91YQ3, NP_055275.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 16786 Da
Antigen Region 76-105 aa
Additional Information
Gene ID 27254
Other Names Cold shock domain-containing protein C2, RNA-binding protein PIPPin, CSDC2, PIPPIN
Target/Specificity This PIPPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human PIPPIN.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPIPPIN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSDC2
Synonyms PIPPIN
Function RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).
Cellular Location Nucleus. Cytoplasm. Note=PIPPin-RNA complexes are located to the nucleus.
Research Areas
Citations (0)

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Background

RNA-binding factor which binds specifically to the very 3'-UTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. Might play a central role in the negative regulation of histone variant synthesis in the developing brain (By similarity).

References

Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :
Schafer, C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4), G726-G734 (2003) :
Raimondi, L., et al. J. Cell. Mol. Med. 7(1):35-42(2003)
Nastasi, T., et al. Neuroreport 11(10):2233-2236(2000)

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$ 295.00
$ 99.00
Cat# AP14318C
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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