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ALDH2 AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1432d | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP1432d-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
ALDH2 Antibody - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | P05091 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 56381 Da |
ALDH2 Antibody - Additional info | |
| Gene ID 217 | |
| Other Names ALDH2; ALDM; Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDHI | |
| Target/Specificity This ALDH2 antibody is generated from rabbits immunized with human ALDH2 recombinant protein. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ALDH2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
ALDH2 Antibody - Protein Information | |
| Name ALDH2 | |
| Synonyms ALDM | |
| Cellular Location Mitochondrion matrix. | |
ALDH2 Antibody - Related products
AP1432a: ALDH2 Antibody (N-term)
AP1432c: ALDH2 Antibody (Center)
RI10230: ALDH2 predesign siRNA
DC01195: Human ALDH2 cDNA Clone
LY11659a: ALDH2 Over-expression Lysate
ALDH2 Antibody - Application data
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Western blot analysis of ALDH2 Antibody (Cat. #AP1432d) in HepG2 cell line lysates (35ug/lane). ALDH2 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human brain tissue reacted with ALDH2 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ALDH2 Antibody (Cat. #AP1432d) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ALDH2 Antibody - Research Areas
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BACKGROUND
ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
REFERENCES
Guo,Y.M., World J. Gastroenterol. 14 (9), 1444-1449 (2008) Chen,L., PLoS Med. 5 (3), E52 (2008) Teeguarden,J.G., Inhal Toxicol 20 (4), 375-390 (2008) Yoshida,A., Pharmacogenetics 2 (4), 139-147 (1992)
