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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   HIGD2A Antibody (N-term)   

HIGD2A Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - HIGD2A Antibody (N-term) AP14331a
    HIGD2A Antibody (N-term) (Cat. #AP14331a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HIGD2A antibody detected the HIGD2A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BW72
Other Accession NP_620175.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 15-44 aa
Additional Information
Other Names HIG1 domain family member 2A, mitochondrial, RCF1 homolog B, RCF1b, HIGD2A
Target/Specificity This HIGD2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human HIGD2A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIGD2A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May be involved in cytochrome c oxidase activity. May play a role in the assembly of respiratory supercomplexes.
Cellular Location Mitochondrion membrane {ECO:0000255|PROSITE- ProRule:PRU00836, ECO:0000269|PubMed:22342701}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00836, ECO:0000269|PubMed:22342701}. Mitochondrion inner membrane EMBL; BC000587; -; NOT_ANNOTATED_CDS; mRNA EMBL; BC007502; AAH07502.1; -; mRNA CCDS; CCDS4401.1; - RefSeq; NP_620175.1; NM_138820.3 UniGene; Hs.534575; - UniGene; Hs.696283; - ProteinModelPortal; Q9BW72; - SMR; Q9BW72; - BioGrid; 128172; 8 IntAct; Q9BW72; 5 iPTMnet; Q9BW72; - PhosphoSitePlus; Q9BW72; - SwissPalm; Q9BW72; - BioMuta; HIGD2A; - DMDM; 74733402; - EPD; Q9BW72; - MaxQB; Q9BW72; - PaxDb; Q9BW72; - PeptideAtlas; Q9BW72; - PRIDE; Q9BW72; - ProteomicsDB; 79260; - TopDownProteomics; Q9BW72; - DNASU; 192286; - Ensembl; ENST00000274787; ENSP00000274787; ENSG00000146066 GeneID; 192286; - KEGG; hsa:192286; - UCSC; uc003meg.4; human CTD; 192286; - DisGeNET; 192286; - EuPathDB; HostDB:ENSG00000146066.2; - GeneCards; HIGD2A; - H-InvDB; HIX0005440; - H-InvDB; HIX0038135; - HGNC; HGNC:28311; HIGD2A HPA; HPA042715; - neXtProt; NX_Q9BW72; - PharmGKB; PA142671685; - eggNOG; KOG4431; Eukaryota eggNOG; ENOG41121ET; LUCA GeneTree; ENSGT00910000144291; - HOGENOM; HOG000234513; - HOVERGEN; HBG054361; - InParanoid; Q9BW72; - OMA; HRGQSQR; - OrthoDB; EOG091G166Q; - PhylomeDB; Q9BW72; - TreeFam; TF314628; - ChiTaRS; HIGD2A; human GenomeRNAi; 192286; - PRO; PR:Q9BW72; - Proteomes; UP000005640; Chromosome 5 Bgee; ENSG00000146066; - CleanEx; HS_HIGD2A; - ExpressionAtlas; Q9BW72; baseline and differential Genevisible; Q9BW72; HS GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW GO; GO:0043066; P:negative regulation of apoptotic process; IDA:MGI GO; GO:0055114; P:oxidation-reduction process; IEA:UniProtKB-KW InterPro; IPR007667; Hypoxia_induced_domain Pfam; PF04588; HIG_1_N; 1 PROSITE; PS51503; HIG1; 1 1: Evidence at protein level; Acetylation; Complete proteome; Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Respiratory chain; Transmembrane; Transmembrane helix; Transport INIT_MET 1 1 Removed. CHAIN 2 106 HIG1 domain family member 2A, mitochondrial /FTId=PRO_0000215777 TRANSMEM 47 67 Helical. {ECO:0000255|PROSITE- ProRule:PRU00836} TRANSMEM 83 103 Helical. {ECO:0000255|PROSITE- ProRule:PRU00836} TOPO_DOM 104 106 Mitochondrial matrix. DOMAIN 20 106 HIG1. {ECO:0000255|PROSITE- ProRule:PRU00836} MOD_RES 2 2 N-acetylalanine SEQUENCE 106 AA; 11529 MW; 205DE0AE39950053 CRC64; MATPGPVIPE VPFEPSKPPV IEGLSPTVYR NPESFKEKFV RKTRENPVVP IGCLATAAAL TYGLYSFHRG NSQRSQLMMR TRIAAQGFTV AAILLGLAVT AMKSRP
Research Areas
Citations (0)

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Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :

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$ 295.00
$ 99.00
Cat# AP14331a
(40 western blots)
Availability: In Stock
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