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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PSMD2 Antibody (N-term)   

PSMD2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PSMD2 Antibody (N-term) AP14349a
    PSMD2 Antibody (N-term) (Cat. #AP14349a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PSMD2 antibody detected the PSMD2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13200
Other Accession NP_002799.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 100200 Da
Antigen Region 6-35 aa
Additional Information
Gene ID 5708
Other Names 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit S2, 26S proteasome subunit p97, Protein 5511, Tumor necrosis factor type 1 receptor-associated protein 2, PSMD2, TRAP2
Target/Specificity This PSMD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human PSMD2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPSMD2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMD2
Synonyms TRAP2
Function Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
Tissue Location Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta
Research Areas
Citations (0)

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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.


Ikeda, Y., et al. J. Biol. Chem. 284(50):34889-34900(2009)
Smith, L., et al. Neoplasia 11(11):1194-1207(2009)
McCauley, J.L., et al. Genes Immun. 10(7):624-630(2009)
Djakovic, S.N., et al. J. Biol. Chem. 284(39):26655-26665(2009)
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)

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$ 295.00
$ 99.00
Cat# AP14349a
(40 western blots)
Availability: In Stock
Bulk Size
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