FOXP4 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q8IVH2 |
Other Accession | Q9DBY0, NP_001012426.1 |
Reactivity | Human |
Predicted | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 73488 Da |
Antigen Region | 522-550 aa |
Gene ID | 116113 |
---|---|
Other Names | Forkhead box protein P4, Fork head-related protein-like A, FOXP4, FKHLA |
Target/Specificity | This FOXP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 522-550 amino acids from the C-terminal region of human FOXP4. |
Dilution | WB~~1:1000 IHC-P~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | FOXP4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FOXP4 |
---|---|
Synonyms | FKHLA |
Function | Transcriptional repressor that represses lung-specific expression. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq].
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Takata, R., et al. Nat. Genet. 42(9):751-754(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Tuovinen, H., et al. J. Immunol. 180(6):3651-3654(2008)
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