|Application ||WB, IHC-P, E|
|Calculated MW||57147 Da|
|Antigen Region||170-199 aa|
|Other Names||Interleukin-9 receptor, IL-9 receptor, IL-9R, CD129, IL9R|
|Target/Specificity||This IL9R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the Central region of human IL9R.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IL9R Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||This is a receptor for interleukin-9.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Secreted|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.
Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
McCanlies, E.C., et al. J. Occup. Environ. Med. 52(7):680-684(2010)
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
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