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TAC3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TAC3 Antibody (Center) AP14366c
    TAC3 Antibody (Center) (Cat. #AP14366c) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the TAC3 antibody detected the TAC3 protein (arrow).
  • IHC-P - TAC3 Antibody (Center) AP14366c
    TAC3 Antibody (Center) (AP14366c)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TAC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHF0
Other Accession NP_001171525.1, NP_037383.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 13438 Da
Antigen Region 54-83 aa
Additional Information
Gene ID 6866
Other Names Tachykinin-3, ZNEUROK1, Neurokinin-B, NKB, Neuromedin-K, TAC3, NKNB
Target/Specificity This TAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the Central region of human TAC3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTAC3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAC3
Synonyms NKNB
Function Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles (By similarity). Is a critical central regulator of gonadal function.
Cellular Location Secreted.
Research Areas
Citations (0)

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This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded protein is primarily expressed in the central and peripheral nervous system and functions as a neurotransmitter. This protein is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternate splicing results in multiple transcript variants.


Klassert, T.E., et al. J. Neuroimmunol. 227 (1-2), 202-207 (2010) :
Hrabovszky, E., et al. Eur. J. Neurosci. 31(11):1984-1998(2010)
Gianetti, E., et al. J. Clin. Endocrinol. Metab. 95(6):2857-2867(2010)
Young, J., et al. J. Clin. Endocrinol. Metab. 95(5):2287-2295(2010)
Semple, R.K., et al. Front Horm Res 39, 133-141 (2010) :

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Cat# AP14366c
(40 western blots)
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