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FRAT1 Antibody (Center)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1436c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
FRAT1 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | Q92837 |
| Other Accession | O75474 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 29093 Da |
FRAT1 Antibody (Center) - Additional info | |
| Gene ID 10023 | |
| Other Names FRAT1; Proto-oncogene FRAT1; Frequently rearranged in advanced T-cell lymphomas 1 | |
| Target/Specificity This FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106~136 amino acids from the Center region of human FRAT1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions FRAT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
FRAT1 Antibody (Center) - Protein Information | |
| Name FRAT1 | |
| Function Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis | |
| Cellular Location Cytoplasm. | |
FRAT1 Antibody (Center) - Related products
AP1436b: FRAT1 Antibody (C-term)
AP1436c: FRAT1 Antibody (Center)
RI12068: FRAT1 predesign siRNA
FRAT1 Antibody (Center) - Application data
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Western blot analysis of FRAT1 (arrow) using rabbit polyclonal FRAT1 Antibody (Center) (Cat.#AP1436c).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the FRAT1 gene (Lane 2) (Origene Technologies).
FRAT1 Antibody (Center) - Research Areas
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BACKGROUND
FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.
REFERENCES
Hagen,T., J. Biol. Chem. 281 (46), 35021-35029 (2006) Wang,Y., Br. J. Cancer 94 (5), 686-691 (2006) Hino,S., J. Biol. Chem. 278 (16), 14066-14073 (2003)
