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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   QPRT Antibody (C-term)   

QPRT Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - QPRT Antibody (C-term) AP14383b
    QPRT Antibody (C-term) (Cat. #AP14383b) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the QPRT antibody detected the QPRT protein (arrow).
  • IHC-P - QPRT Antibody (C-term) AP14383b
    QPRT Antibody (C-term) (AP14383b)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of QPRT Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15274
Other Accession NP_055113.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 30846 Da
Antigen Region 206-234 aa
Additional Information
Gene ID 23475
Other Names Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase, QPRT
Target/Specificity This QPRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsQPRT Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Involved in the catabolism of quinolinic acid (QA).
Research Areas
Citations (0)

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This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.


Hinsch, N., et al. BMC Cancer 9, 93 (2009) :
Liu, H., et al. J. Mol. Biol. 373(3):755-763(2007)
Magni, G., et al. Cell. Mol. Life Sci. 61(1):19-34(2004)
Fukuoka, S., et al. Adv. Exp. Med. Biol. 467, 611-614 (1999) :
Fukuoka, S.I., et al. Biochim. Biophys. Acta 1395(2):192-201(1998)

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$ 295.00
$ 99.00
Cat# AP14383b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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