|Application ||IF, WB, IHC-P, E|
|Other Accession||Q61345, NP_004463.1|
|Calculated MW||46140 Da|
|Antigen Region||1-30 aa|
|Other Names||Forkhead box protein D1, Forkhead-related protein FKHL8, Forkhead-related transcription factor 4, FREAC-4, FOXD1, FKHL8, FREAC4|
|Target/Specificity||This FOXD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FOXD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FOXD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor required for formation of positional identity in the developing retina, regionalization of the optic chiasm and morphogenesis of the kidney. Can neuralize ectodermal cells directly (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
This intronless gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in tumor formation.
Berg, D.T., et al. J. Biol. Chem. 280(15):14943-14947(2005)
Ernstsson, S., et al. J. Biol. Chem. 271(35):21094-21099(1996)
Larsson, C., et al. Genomics 30(3):464-469(1995)
Pierrou, S., et al. EMBO J. 13(20):5002-5012(1994)
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