|Application ||WB, E|
|Other Accession||NP_006231.2, NP_689410.1|
|Calculated MW||75792 Da|
|Antigen Region||298-327 aa|
|Other Names||Serine/threonine-protein phosphatase with EF-hands 1, PPEF-1, Protein phosphatase with EF calcium-binding domain, PPEF, Serine/threonine-protein phosphatase 7, PP7, PPEF1, PPEF, PPP7C|
|Target/Specificity||This PPEF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-327 amino acids from the Central region of human PPEF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PPEF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a role in the recovery or adaptation response of photoreceptors. May have a role in development.|
|Tissue Location||Detected in retina and retinal derived Y-79 retinoblastoma cells. Also found in fetal brain|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described.
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Hillman, R.T., et al. Genome Biol. 5 (2), R8 (2004) :
Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
Kutuzov, M.A., et al. Biochem. Biophys. Res. Commun. 293(3):1047-1052(2002)
Ramulu, P., et al. Mol. Cell. Biol. 21(24):8605-8614(2001)
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