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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   RCAN3 Antibody (C-term)   

RCAN3 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - RCAN3 Antibody (C-term) AP14397b
    RCAN3 Antibody (C-term) (Cat. #AP14397b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RCAN3 antibody detected the RCAN3 protein (arrow).
  • IHC-P - RCAN3 Antibody (C-term) AP14397b
    RCAN3 Antibody (C-term) (AP14397b)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RCAN3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UKA8
Other Accession NP_038469.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27492 Da
Antigen Region 194-222 aa
Additional Information
Gene ID 11123
Other Names Calcipressin-3, Down syndrome candidate region 1-like protein 2, Myocyte-enriched calcineurin-interacting protein 3, MCIP3, Regulator of calcineurin 3, RCAN3, DSCR1L2
Target/Specificity This RCAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 amino acids from the C-terminal region of human RCAN3.
Dilution WB~~1:1000
IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRCAN3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RCAN3
Synonyms DSCR1L2
Function Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Tissue Location Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues
Research Areas
Citations (0)

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Background

RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).

References

Sales, K.J., et al. Biochim. Biophys. Acta 1793(12):1917-1928(2009)
Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)
Facchin, F., et al. Gene 407 (1-2), 159-168 (2008) :
Mulero, M.C., et al. Biochim. Biophys. Acta 1773(3):330-341(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 295.00
$ 99.00
Cat# AP14397b
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Quantity:
(40 western blots)
Availability: In Stock
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