|Application ||WB, IHC-P, E|
|Calculated MW||27492 Da|
|Antigen Region||194-222 aa|
|Other Names||Calcipressin-3, Down syndrome candidate region 1-like protein 2, Myocyte-enriched calcineurin-interacting protein 3, MCIP3, Regulator of calcineurin 3, RCAN3, DSCR1L2|
|Target/Specificity||This RCAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 194-222 amino acids from the C-terminal region of human RCAN3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RCAN3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).|
|Tissue Location||Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Sales, K.J., et al. Biochim. Biophys. Acta 1793(12):1917-1928(2009)
Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008)
Facchin, F., et al. Gene 407 (1-2), 159-168 (2008) :
Mulero, M.C., et al. Biochim. Biophys. Acta 1773(3):330-341(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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