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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SENP5 Antibody (C-term)   

SENP5 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SENP5 Antibody (C-term) AP14400b
    SENP5 Antibody (C-term) (Cat. #AP14400b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the SENP5 antibody detected the SENP5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96HI0
Other Accession Q6NXL6, Q8WP32, NP_689912.2
Reactivity Human
Predicted Monkey, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 86693 Da
Antigen Region 718-747 aa
Additional Information
Gene ID 205564
Other Names Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5, SENP5
Target/Specificity This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human SENP5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSENP5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SENP5
Function Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division.
Cellular Location Nucleus, nucleolus
Research Areas
Citations (0)

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The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).


Yun, C., et al. J. Cell Biol. 183(4):589-595(2008)
Ding, X., et al. Oncol. Rep. 20(5):1041-1045(2008)
Gong, L., et al. J. Biol. Chem. 281(23):15869-15877(2006)
Di Bacco, A., et al. Mol. Cell. Biol. 26(12):4489-4498(2006)
Yeh, E.T., et al. Gene 248 (1-2), 1-14 (2000) :

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Cat# AP14400b
(40 western blots)
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