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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTPRE Antibody (N-term)   

PTPRE Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTPRE Antibody (N-term) AP14405a
    PTPRE Antibody (N-term) (Cat. #AP14405a) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PTPRE antibody detected the PTPRE protein (arrow).
  • IHC-P - PTPRE Antibody (N-term) AP14405a
    PTPRE Antibody (N-term) (AP14405a)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PTPRE Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23469
Other Accession B2GV87, P49446, NP_569119.1, NP_006495.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 80642 Da
Antigen Region 134-163 aa
Additional Information
Gene ID 5791
Other Names Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
Target/Specificity This PTPRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 amino acids from the N-terminal region of human PTPRE.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTPRE Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cytoplasm.
Tissue Location Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells)
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq].


Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Barr, A.J., et al. Cell 136(2):352-363(2009)
Kraut-Cohen, J., et al. J. Biol. Chem. 283(8):4612-4621(2008)
Tremblay, K., et al. PLoS ONE 3 (8), E2907 (2008) :

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$ 295.00
$ 99.00
Cat# AP14405a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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