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GNAI2 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP14419a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14419a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
GNAI2 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | P04899 |
| Other Accession | Q4R592, NP_002061.1 |
| Reactivity | Human |
| Predicted | Monkey |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 40451 Da |
GNAI2 Antibody (N-term) - Additional info | |
| Gene ID 2771 | |
| Other Names GNAI2; GNAI2B; Guanine nucleotide-binding protein G(i) subunit alpha-2; Adenylate cyclase-inhibiting G alpha protein | |
| Target/Specificity This GNAI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-107 amino acids from the N-terminal region of human GNAI2. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions GNAI2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
GNAI2 Antibody (N-term) - Protein Information | |
| Name GNAI2 | |
| Synonyms GNAI2B | |
| Function Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division | |
| Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cell membrane. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody | |
GNAI2 Antibody (N-term) - Related products
AP14419a: GNAI2 Antibody (N-term)
RI12257: GNAI2 predesign siRNA
DC03911: Human GNAI2 cDNA Clone
LY12583a: GNAI2 Over-expression Lysate
GNAI2 Antibody (N-term) - Application data
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GNAI2 Antibody (N-term) (Cat. #AP14419a) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the GNAI2 antibody detected the GNAI2 protein (arrow).
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Western blot analysis of GNAI2 (arrow) using rabbit polyclonal GNAI2 Antibody (N-term) (Cat. #AP14419a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GNAI2 gene.
GNAI2 Antibody (N-term) - Research Areas
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BACKGROUND
The protein encoded by this gene is an alpha subunit of guanine nucleotide binding proteins (G proteins). The encoded protein contains the guanine nucleotide binding site and is involved in the hormonal regulation of adenylate cyclase. Several transcript variants encoding different isoforms have been detected for this gene, but the full-length nature of only two are known so far.
REFERENCES
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) So, H.C., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (1), 103-113 (2010) : Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Kuszak, A.J., et al. J. Biol. Chem. 284(39):26732-26741(2009) Huang, X., et al. Med. Hypotheses 73(1):56-59(2009)
