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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Mouse Mapk4 Antibody (N-term)   

Mouse Mapk4 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Mapk4 Antibody (N-term) AP14445a
    Mouse Mapk4 Antibody (N-term) (Cat. #AP14445a) western blot analysis in C6 cell line lysates (35ug/lane).This demonstrates the Mapk4 antibody detected the Mapk4 protein (arrow).
  • WB - Mouse Mapk4 Antibody (N-term) AP14445a
    Mouse Mapk4 Antibody (N-term) (Cat. #AP14445a) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Mapk4 antibody detected the Mapk4 protein (arrow).
  • IHC-P - Mouse Mapk4 Antibody (N-term) AP14445a
    Mouse Mapk4 Antibody (N-term) (AP14445a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Mapk4 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6P5G0
Other Accession Q63454, NP_766220.2
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 65574 Da
Antigen Region 67-94 aa
Additional Information
Gene ID 225724
Other Names Mitogen-activated protein kinase 4, MAP kinase 4, MAPK 4, Extracellular signal-regulated kinase 4, ERK-4, Mapk4, Erk4, Prkm4
Target/Specificity This Mouse Mapk4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the N-terminal region of mouse Mapk4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Mapk4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Mapk4
Synonyms Erk4, Prkm4
Function Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.
Cellular Location Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following interaction with MAPKAPK5
Research Areas
Citations (0)

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Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle (By similarity).


Klinger, S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(39):16710-16715(2009)
Kesavan, C., et al. Bone 41(2):223-230(2007)
Kant, S., et al. J. Biol. Chem. 281(46):35511-35519(2006)
Zambrowicz, B.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(24):14109-14114(2003)
Xu, H., et al. J. Biol. Chem. 278(32):30187-30192(2003)

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Cat# AP14445a
(40 western blots)
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