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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SSR1 Antibody (N-term)   

SSR1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - SSR1 Antibody (N-term) AP1444a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with SSR1 antibody (N-term) (Cat.#AP1444a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • WB - SSR1 Antibody (N-term) AP1444a
    Western blot analysis of SSR1 (arrow) using rabbit SSR1 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SSR1 gene (Lane 2) (Origene Technologies).
  • WB - SSR1 Antibody (N-term) AP1444a
    SSR1 Antibody (N-term) (Cat. #AP1444a) western blot analysis in Hela,mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the SSR1 antibody detected the SSR1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P43307
Other Accession A6QLP7
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32235 Da
Antigen Region 17-46 aa
Additional Information
Gene ID 6745
Other Names Translocon-associated protein subunit alpha, TRAP-alpha, Signal sequence receptor subunit alpha, SSR-alpha, SSR1, TRAPA
Target/Specificity This SSR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human SSR1.
Dilution IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSSR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSR1
Synonyms TRAPA
Function TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins.
Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are exclusively non-canonical.


Hirama, T., et al., FEBS Lett. 455(3):223-227 (1999).
Hartmann, E., et al., FEBS Lett. 349(3):324-326 (1994).

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$ 295.00
$ 99.00
Cat# AP1444a
(40 western blots)
Availability: In Stock
Bulk Size
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