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OTUB2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OTUB2 Antibody (N-term) AP14463a
    OTUB2 Antibody (N-term) (Cat. #AP14463a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the OTUB2 antibody detected the OTUB2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96DC9
Other Accession NP_075601.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27213 Da
Antigen Region 19-48 aa
Additional Information
Gene ID 78990
Other Names Ubiquitin thioesterase OTUB2, Deubiquitinating enzyme OTUB2, OTU domain-containing ubiquitin aldehyde-binding protein 2, Otubain-2, Ubiquitin-specific-processing protease OTUB2, OTUB2, C14orf137, OTB2, OTU2
Target/Specificity This OTUB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human OTUB2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOTUB2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OTUB2
Synonyms C14orf137, OTB2, OTU2
Function Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of 'Lys-11'-,'Lys-48'- and 'Lys-63'- linked polyubiquitin chains, with a preference for 'Lys-63'-linked polyubiquitin chains.
Tissue Location Widely expressed. Expressed at higher level in brain.
Research Areas
Citations (0)

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Otubains are deubiquitylating cysteine proteases (DUBs; see MIM 602519) that belong to the ovarian tumor (OTU) protein superfamily. Like other DUBs, otubains cleave proteins precisely at the ubiquitin (UB; see MIM 191339)-protein bond.


Li, S., et al. J. Biol. Chem. 285(7):4291-4297(2010)
Sowa, M.E., et al. Cell 138(2):389-403(2009)
Edelmann, M.J., et al. Biochem. J. 418(2):379-390(2009)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Nanao, M.H., et al. EMBO Rep. 5(8):783-788(2004)

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Cat# AP14463a
(40 western blots)
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