|Application ||WB, E|
|Calculated MW||124583 Da|
|Antigen Region||361-389 aa|
|Other Names||Tyrosine-protein kinase receptor Tie-1, Tie1, Tie, Tie-1|
|Target/Specificity||This Mouse Tie1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361-389 amino acids from the Central region of mouse Tie1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Tie1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Specifically expressed in developing vascular endothelial cells. Abundantly expressed in lung and heart, moderately in brain, liver and kidney, and weakly in thymus, spleen and testis.|
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Probable protein tyrosine-kinase transmembrane receptor.
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