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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   TDT Antibody (N-term)   

TDT Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TDT Antibody (N-term) AP14478a
    TdT Antibody (N-term) (Cat. #AP14478a) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TdT antibody detected the TdT protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04053
Other Accession P09838, P06526, NP_001017520.1, NP_004079.3
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 58536 Da
Antigen Region 42-70 aa
Additional Information
Gene ID 1791
Other Names DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase, DNTT, TDT
Target/Specificity This TDT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TDT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTDT Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TDT {ECO:0000303|PubMed:11473582}
Function Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.


Kubota, T., et al. Genes Cells 12(8):941-959(2007)
O'Malley, D.P., et al. Haematologica 91(8):1139-1140(2006)
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Thai, T.H., et al. J. Immunol. 173(6):4009-4019(2004)
Liu, L., et al. Am. J. Clin. Pathol. 121(6):810-815(2004)

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$ 295.00
$ 99.00
Cat# AP14478a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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