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COL1A1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - COL1A1 Antibody (C-term) AP14490b
    COL1A1 Antibody (C-term) (Cat. #AP14490b) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the COL1A1 antibody detected the COL1A1 protein (arrow).
  • IHC-P - COL1A1 Antibody (C-term) AP14490b
    COL1A1 Antibody (C-term) (Cat. #AP14490b)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COL1A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02452
Other Accession P02454, P11087, P02457, P02453, NP_000079.2
Reactivity Human, Mouse
Predicted Bovine, Chicken, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 138941 Da
Antigen Region 1077-1106 aa
Additional Information
Gene ID 1277
Other Names Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
Target/Specificity This COL1A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1077-1106 amino acids from the C-terminal region of human COL1A1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOL1A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name COL1A1
Function Type I collagen is a member of group I collagen (fibrillar forming collagen).
Cellular Location Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}
Tissue Location Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite
Research Areas
Citations (0)

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This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish].


Blades, H.Z., et al. Bone 47(5):989-994(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Jin, H., et al. Osteoporos Int (2010) In press : Szczesny, G., et al. Arch Orthop Trauma Surg (2010) In press : Cheung, M.S., et al. J. Bone Miner. Res. (2010) In press :

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Cat# AP14490b
(40 western blots)
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