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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PSMA5 Antibody (N-term)   

PSMA5 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PSMA5 Antibody (N-term) AP1449a
    Western blot analysis of PSMA5 (arrow) using rabbit polyclonal PSMA5 Antibody (N-term) (Cat.#AP1449a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PSMA5 gene (Lane 2) (Origene Technologies).
  • IHC-P - PSMA5 Antibody (N-term) AP1449a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PSMA5 antibody (N-term)(Cat.#AP1449a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28066
Other Accession P34064, Q9Z2U1, Q95083, Q95008, Q5E987
Reactivity Human
Predicted Bovine, C.Elegans, Drosophila, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 26411 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 5686
Other Names Proteasome subunit alpha type-5, Macropain zeta chain, Multicatalytic endopeptidase complex zeta chain, Proteasome zeta chain, PSMA5
Target/Specificity This PSMA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PSMA5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPSMA5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PSMA5
Function The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Expressed in fetal brain (at protein level).
Research Areas
Citations (0)

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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PMA5 is a member of the peptidase T1A family, that is a 20S core alpha subunit.


Beausoleil,S.A., Nat. Biotechnol. 24 (10), 1285-1292 (2006)
Gregory,S.G., Nature 441 (7091), 315-321 (2006)
Beausoleil,S.A., Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
Conticello,S.G., Curr. Biol. 13 (22), 2009-2013 (2003)
Yu,X., Science 302 (5647), 1056-1060 (2003)

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$ 295.00
$ 99.00
Cat# AP1449a
(40 western blots)
Availability: In Stock
Bulk Size
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