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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RIT1 Antibody (N-term)   

RIT1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RIT1 Antibody (N-term) AP14501a
    RIT1 Antibody (N-term) (Cat. #AP14501a) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the RIT1 antibody detected the RIT1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q92963
Other Accession P70426, NP_008843.1
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25145 Da
Antigen Region 41-70 aa
Additional Information
Gene ID 6016
Other Names GTP-binding protein Rit1, Ras-like protein expressed in many tissues, Ras-like without CAAX protein 1, RIT1, RIBB, RIT, ROC1
Target/Specificity This RIT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the N-terminal region of human RIT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRIT1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RIT1
Synonyms RIBB, RIT, ROC1
Function Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF- dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.
Cellular Location Cell membrane.
Tissue Location Expressed in many tissues.
Research Areas
Citations (0)

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RIT belongs to the RAS (HRAS; MIM 190020) subfamily of small GTPases (Hynds et al., 2003 [PubMed 12668729]).[supplied by OMIM].


Lee, Y.R., et al. EMBO J. 29(10):1748-1761(2010)
Katiyar, S., et al. EMBO Rep. 10(8):866-872(2009)
Sonuga-Barke, E.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :
Hu, J., et al. Genes Dev. 22(7):866-871(2008)
Wu, C., et al. Proteomics 7(11):1775-1785(2007)

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$ 295.00
$ 99.00
Cat# AP14501a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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