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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   RFXAP Antibody (C-term)   

RFXAP Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RFXAP Antibody (C-term) AP14506b
    RFXAP Antibody (C-term) (Cat. #AP14506b) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the RFXAP antibody detected the RFXAP protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00287
Other Accession Q8VCG9, NP_000529.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28232 Da
Antigen Region 196-225 aa
Additional Information
Gene ID 5994
Other Names Regulatory factor X-associated protein, RFX-associated protein, RFX DNA-binding complex 36 kDa subunit, RFXAP
Target/Specificity This RFXAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human RFXAP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRFXAP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Part of the RFX complex that binds to the X-box of MHC II promoters.
Cellular Location Nucleus.
Tissue Location Ubiquitous.
Research Areas
Citations (0)

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Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.


Laird, K.M., et al. J. Mol. Biol. 403(1):40-51(2010)
Bushway, M., et al. Immunogenetics 62(2):109-116(2010)
Briggs, L., et al. Proteins 76(3):655-664(2009)
Garvie, C.W., et al. Biochim. Biophys. Acta 1779(12):797-804(2008)
van Eggermond, M.C., et al. Mol. Immunol. 45(10):2920-2928(2008)

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$ 295.00
$ 99.00
Cat# AP14506b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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