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PRDM1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - PRDM1 Antibody (N-term) AP14521a
    PRDM1 Antibody (N-term) (Cat. #AP14521a) western blot analysis in HL-60 cell line and mouse spleen tissue lysates (35ug/lane).This demonstrates the PRDM1 antibody detected the PRDM1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75626
Other Accession Q60636, NP_001189.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 91771 Da
Antigen Region 106-134 aa
Additional Information
Gene ID 639
Other Names PR domain zinc finger protein 1, 211-, BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1, Positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, PRDM1, BLIMP1
Target/Specificity This PRDM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human PRDM1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRDM1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDM1
Synonyms BLIMP1
Function Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm
Research Areas
Citations ( 0 )


This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported.


Smith, M.A., et al. J. Immunol. 185(10):6058-6067(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Hangaishi, A., et al. Int. J. Hematol. 91(1):46-53(2010)
Garcia-Bates, T.M., et al. J. Immunol. 183(11):6903-6912(2009)
Raychaudhuri, S., et al. Nat. Genet. 41(12):1313-1318(2009)

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$ 295.00
$ 99.00
Cat# AP14521a
(40 western blots)
Availability: In Stock
Bulk Size
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