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SFTPA1B Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP14524c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14524c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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SFTPA1B Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q8IWL2 |
| Other Accession | Q8IWL1, NP_001087239.2, NP_005402.3 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 26242 Da |
SFTPA1B Antibody (Center) - Additional info | |
| Gene ID 653509 | |
| Other Names SFTPA1; COLEC4; PSAP; SFTP1; SFTPA; SFTPA1B; Pulmonary surfactant-associated protein A1; 35 kDa pulmonary surfactant-associated protein; Alveolar proteinosis protein; Collectin-4 | |
| Target/Specificity This SFTPA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the Central region of human SFTPA1B. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions SFTPA1B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
SFTPA1B Antibody (Center) - Protein Information | |
| Name SFTPA1 | |
| Synonyms COLEC4, PSAP, SFTP1, SFTPA, SFTPA1B | |
| Function In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration | |
| Cellular Location Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film | |
SFTPA1B Antibody (Center) - Related products
SFTPA1B Antibody (Center) - Application data
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SFTPA1B Antibody (Center) (Cat. #AP14524c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SFTPA1B antibody detected the SFTPA1B protein (arrow).
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SFTPA1B Antibody (Center) (AP14524c)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung adenocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SFTPA1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
SFTPA1B Antibody (Center) - Research Areas
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BACKGROUND
This gene encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants.
REFERENCES
Silveyra, P., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (4), L523-L534 (2010) : Liu, D.Y., et al. Zhongguo Dang Dai Er Ke Za Zhi 12(6):444-446(2010) Liu, J., et al. Tohoku J. Exp. Med. 221(1):35-42(2010) Berg, T., et al. Biochim. Biophys. Acta 1543(1):159-173(2000) Childs, R.A., et al. J. Biol. Chem. 267(14):9972-9979(1992)