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STS Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P08842 |
| Other Accession | NP_000342.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 65492 Da |
| Antigen Region | 488-517 aa |
| Gene ID | 412 |
|---|---|
| Other Names | Steryl-sulfatase, Arylsulfatase C, ASC, Steroid sulfatase, Steryl-sulfate sulfohydrolase, STS, ARSC1 |
| Target/Specificity | This STS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 488-517 amino acids from the C-terminal region of human STS. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | STS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | STS |
|---|---|
| Synonyms | ARSC1 |
| Function | Catalyzes the conversion of sulfated steroid precursors, such as dehydroepiandrosterone sulfate (DHEA-S) and estrone sulfate to the free steroid. |
| Cellular Location | Cytoplasmic vesicle, secretory vesicle, microneme membrane; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).
References
Chanplakorn, N., et al. Breast Cancer Res. Treat. 120(3):639-648(2010)
Gruber, R., et al. J. Dermatol. Sci. 58(1):72-75(2010)
Canueto, J., et al. J Eur Acad Dermatol Venereol (2010) In press :
Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :
Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)
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