|Application ||WB, IHC-P, E|
|Calculated MW||65492 Da|
|Antigen Region||488-517 aa|
|Other Names||Steryl-sulfatase, Arylsulfatase C, ASC, Steroid sulfatase, Steryl-sulfate sulfohydrolase, STS, ARSC1|
|Target/Specificity||This STS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 488-517 amino acids from the C-terminal region of human STS.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Conversion of sulfated steroid precursors to estrogens during pregnancy.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI).
Chanplakorn, N., et al. Breast Cancer Res. Treat. 120(3):639-648(2010)
Gruber, R., et al. J. Dermatol. Sci. 58(1):72-75(2010)
Canueto, J., et al. J Eur Acad Dermatol Venereol (2010) In press :
Li, J., et al. Breast Cancer Res. 12 (2), R19 (2010) :
Chakrabarti, B., et al. Autism Res 2(3):157-177(2009)
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