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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   SNRPN Antibody (N-term)   

SNRPN Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNRPN Antibody (N-term) AP14532a
    SNRPN Antibody (N-term) (Cat. #AP14532a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SNRPN antibody detected the SNRPN protein (arrow).
  • IHC-P - SNRPN Antibody (N-term) AP14532a
    SNRPN Antibody (N-term) (AP14532a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SNRPN Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P63162
Other Accession P63164, P63163, Q60HD3, Q17QN3, NP_073716.1, NP_073717.1
Reactivity Human
Predicted Bovine, Monkey, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24614 Da
Antigen Region 34-62 aa
Additional Information
Gene ID 6638
Other Names Small nuclear ribonucleoprotein-associated protein N, snRNP-N, Sm protein D, Sm-D, Sm protein N, Sm-N, SmN, Tissue-specific-splicing protein, SNRPN, HCERN3, SMN
Target/Specificity This SNRPN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-62 amino acids from the N-terminal region of human SNRPN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNRPN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HCERN3, SMN
Function May be involved in tissue-specific alternative RNA processing events.
Cellular Location Nucleus.
Tissue Location Expressed in brain and lymphoblasts.
Research Areas
Citations (0)

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The protein encoded by this gene is one polypeptide of a small nuclear ribonucleoprotein complex and belongs to the snRNP SMB/SMN family. The protein plays a role in pre-mRNA processing, possibly tissue-specific alternative splicing events. Although individual snRNPs are believed to recognize specific nucleic acid sequences through RNA-RNA base pairing, the specific role of this family member is unknown. The protein arises from a bicistronic transcript that also encodes a protein identified as the SNRPN upstream reading frame (SNURF). Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region. Additional splice variants have been described but sequences for the complete transcripts have not been determined. The 5' UTR of this gene has been identified as an imprinting center. Alternative splicing or deletion caused by a translocation event in this paternally-expressed region is responsible for Angelman syndrome or Prader-Willi syndrome due to parental imprint switch failure.


Benetatos, L., et al. Leuk. Res. 34(2):148-153(2010)
Kim, S.J., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (7), 1116-1125 (2008) :
Horsthemke, B., et al. Am. J. Med. Genet. A 146A (16), 2041-2052 (2008) :
Runte, M., et al. Hum. Mol. Genet. 10(23):2687-2700(2001)
Kuslich, C.D., et al. Am. J. Hum. Genet. 64(1):70-76(1999)

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$ 295.00
$ 99.00
Cat# AP14532a
(40 western blots)
Availability: In Stock
Bulk Size
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