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NRF1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NRF1 Antibody (Center) AP14535c
    NRF1 Antibody (Center) (Cat. #AP14535c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NRF1 antibody detected the NRF1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16656
Other Accession Q9WU00, Q90X44, NP_005002.3, NP_001035199.1
Reactivity Human
Predicted Zebrafish, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53541 Da
Antigen Region 226-255 aa
Additional Information
Gene ID 4899
Other Names Nuclear respiratory factor 1, NRF-1, Alpha palindromic-binding protein, Alpha-pal, NRF1
Target/Specificity This NRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-255 amino acids from the Central region of human NRF1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNRF1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRF1
Function Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed with strongest expression in skeletal muscle
Research Areas
Citations (0)

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This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized. Additional variants encoding different protein isoforms have been described but they have not been fully characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.


Gonen, N., et al. J. Biol. Chem. 285(44):33602-33613(2010)
Zhang, Y., et al. Biochem. J. 430(3):497-510(2010)
Shao, D., et al. Mitochondrion 10(5):516-527(2010)
Adam, T., et al. Biochem. Biophys. Res. Commun. 398(3):495-499(2010)
Spelbrink, J.N., et al. Hum. Mol. Genet. 4(9):1591-1596(1995)

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$ 295.00
$ 99.00
Cat# AP14535c
(40 western blots)
Availability: In Stock
Bulk Size
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