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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PPP6C Antibody (C-term)   

PPP6C Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PPP6C Antibody (C-term) AP14562b
    Anti-PPP6C Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 35 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - PPP6C Antibody (C-term) AP14562b
    PPP6C Antibody (C-term) (Cat. #AP14562b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PPP6C antibody detected the PPP6C protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00743
Other Accession Q64620, Q9CQR6, NP_001116841.1, NP_002712.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35144 Da
Antigen Region 264-293 aa
Additional Information
Gene ID 5537
Other Names Serine/threonine-protein phosphatase 6 catalytic subunit, PP6C, Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed, PPP6C, PPP6
Target/Specificity This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-293 amino acids from the C-terminal region of human PPP6C.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPP6C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP6C
Synonyms PPP6
Function Catalytic subunit of protein phosphatase 6 (PP6). PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.
Cellular Location Cytoplasm
Tissue Location Ubiquitously expressed in all tissues tested with highest expression levels in testis, heart, kidney, brain, stomach, liver and skeletal muscle and lowest in placenta, lung colon and spleen.
Research Areas
Citations (0)

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This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X.


Douglas, P., et al. Mol. Cell. Biol. 30(6):1368-1381(2010)
Dema, B., et al. Genes Immun. 10(7):659-661(2009)
Morales-Johansson, H., et al. PLoS ONE 4 (7), E6331 (2009) :
Mi, J., et al. PLoS ONE 4 (2), E4395 (2009) :
Stefansson, B., et al. Biochemistry 47(5):1442-1451(2008)

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$ 295.00
$ 99.00
Cat# AP14562b
(40 western blots)
Availability: In Stock
Bulk Size
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