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DUSP15 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9H1R2 |
| Other Accession | NP_817130.1, NP_001012662.1, NP_542178.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 31882 Da |
| Antigen Region | 125-153 aa |
| Gene ID | 128853 |
|---|---|
| Other Names | Dual specificity protein phosphatase 15, VH1-related member Y, Vaccinia virus VH1-related dual-specific protein phosphatase Y, DUSP15, C20orf57, VHY |
| Target/Specificity | This DUSP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-153 amino acids from the Central region of human DUSP15. |
| Dilution | WB~~1:1000 IHC-P~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DUSP15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DUSP15 (HGNC:16236) |
|---|---|
| Function | May dephosphorylate MAPK13, ATF2, ERBB3, PDGFRB and SNX6 (PubMed:22792334). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Highly expressed in testis (PubMed:15138252). Expressed in brain; up-regulated in patients with multiple sclerosis gray matter lesions (PubMed:22792334). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene belongs to the non-receptor class of the protein-tyrosine phosphatase family. The encoded protein has both protein-tyrosine phophatase activity and serine/threonine-specific phosphatase activity, and therefore is known as a dual specificity phosphatase. Three transcript variants encoding two different isoforms have been found for this gene.
References
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Yoon, T.S., et al. Proteins 61(3):694-697(2005)
Alonso, A., et al. J. Biol. Chem. 279(31):32586-32591(2004)
Alonso, A., et al. J. Biol. Chem. 279(31):32586-32591(2004)
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