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PGF Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PGF Antibody (Center) AP14578c
    PGF Antibody (Center) (Cat. #AP14578c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PGF antibody detected the PGF protein (arrow).
  • IHC-P - PGF Antibody (Center) AP14578c
    PGF Antibody (Center) (AP14578c)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PGF Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49763
Other Accession NP_002623.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 24789 Da
Antigen Region 120-148 aa
Additional Information
Gene ID 5228
Other Names Placenta growth factor, PlGF, PGF, PGFL, PLGF
Target/Specificity This PGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human PGF.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPGF Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PGF
Synonyms PGFL, PLGF
Function Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
Cellular Location Secreted. Note=The three isoforms are secreted but PlGF-2 appears to remain cell attached unless released by heparin
Tissue Location While the three isoforms are present in most placental tissues, PlGF-2 is specific to early (8 week) placenta and only PlGF-1 is found in the colon and mammary carcinomas
Research Areas
Citations (0)

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The PGF gene encodes placenta growth factor, a homolog of vascular endothelial growth factor (VEGFA; MIM 192240), that selectively binds to VEGFR1 (FLT1; MIM 165070) and is involved in angiogenesis (Fischer et al., 2007 [PubMed 17981115]; Bais et al., 2010 [PubMed 20371352]).


Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) :
Cowans, N.J., et al. Prenat. Diagn. 30(6):565-570(2010)
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Andersson, M.K., et al. BMC Cancer 10, 249 (2010) :
Pan, P., et al. BMC Cell Biol. 11, 36 (2010) :

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$ 295.00
$ 99.00
Cat# AP14578c
(40 western blots)
Availability: In Stock
Bulk Size
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