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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   SCGN Antibody (N-term)   

SCGN Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SCGN Antibody (N-term) AP1458a
    Western blot analysis of *SCGN (arrow) using rabbit polyclonal *SCGN Antibody (N-term) (Cat.#AP1458a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the *SCGN gene.
  • IHC-P - SCGN Antibody (N-term) AP1458a
    SCGN Antibody (N-term) (Cat. #AP1458a)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SCGN Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - SCGN Antibody (N-term) AP1458a
    SCGN) Antibody (N-term) (Cat. #AP1458a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O76038
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32040 Da
Antigen Region 54-84 aa
Additional Information
Gene ID 10590
Other Names Secretagogin, SCGN, SECRET
Target/Specificity This SCGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-84 amino acids from the N-terminal region of human SCGN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSCGN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SECRET
Cellular Location Cytoplasm. Secreted. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity). Detectable in human serum after ischemic neuronal damage.
Tissue Location Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons.
Research Areas
Citations (0)

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SCGN is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. SCGN is thought to be involved in KCL-stimulated calcium flux and cell proliferation.


Skovhus,K.V., Scand. J. Immunol. 64 (6), 639-645 (2006)
Zierhut,B., Biochem. Biophys. Res. Commun. 329 (4), 1193-1199 (2005)
Mungall,A.J., Nature 425 (6960), 805-811 (2003)
Zhan,X., Pituitary 6 (4), 189-202 (2003)

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$ 295.00
$ 99.00
Cat# AP1458a
(40 western blots)
Availability: In Stock
Bulk Size
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