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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   SNAP23 Antibody (C-term)   

SNAP23 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNAP23 Antibody (C-term) AP14590b
    SNAP23 Antibody (C-term) (Cat. #AP14590b) western blot analysis in human placenta tissue lysates (35ug/lane).This demonstrates the SNAP23 antibody detected the SNAP23 protein (arrow).
  • WB - SNAP23 Antibody (C-term) AP14590b
    Western blot analysis of SNAP23 (arrow) using rabbit polyclonal SNAP23 Antibody (C-term) (Cat. #AP14590b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the SNAP23 gene.
  • IHC-P - SNAP23 Antibody (C-term) AP14590b
    SNAP23 Antibody (C-term) (AP14590b)immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SNAP23 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00161
Other Accession NP_003816.2, NP_570710.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 23354 Da
Antigen Region 170-199 aa
Additional Information
Gene ID 8773
Other Names Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23, SNAP23
Target/Specificity This SNAP23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the C-terminal region of human SNAP23.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNAP23 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNAP23
Function Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
Cellular Location Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Cell junction, synapse, synaptosome Note=Mainly localized to the plasma membrane
Tissue Location Ubiquitous. Highest levels where found in placenta
Research Areas
Citations (0)

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Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene.


Greaves, J., et al. J. Biol. Chem. 285(32):24629-24638(2010)
Bostrom, P., et al. Diabetes 59(8):1870-1878(2010)
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :
Gratacos, M., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009) :

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$ 295.00
$ 99.00
Cat# AP14590b
(40 western blots)
Availability: In Stock
Bulk Size
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