|Application ||WB, IHC-P, E|
|Calculated MW||80641 Da|
|Antigen Region||180-209 aa|
|Other Names||Mitochondrial intermediate peptidase, MIP, MIPEP, MIP|
|Target/Specificity||This MIPEP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-209 amino acids from the N-terminal region of human MIPEP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MIPEP Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cleaves proteins, imported into the mitochondrion, to their mature size.|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
MIPEP performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This protein may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia.
Chew A., Genomics 40:493-496(1997).
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