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Mouse Dyrk1b Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Mouse Dyrk1b Antibody (Center) AP14617c
    Mouse Dyrk1b Antibody (Center) (Cat. #AP14617c) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Dyrk1b antibody detected the Dyrk1b protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Z188
Other Accession Q9Y463, NP_001033046.1, NP_034222.1
Reactivity Mouse
Predicted Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 69178 Da
Antigen Region 376-403 aa
Additional Information
Gene ID 13549
Other Names Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Dyrk1b
Target/Specificity This Mouse Dyrk1b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 376-403 amino acids from the Central region of mouse Dyrk1b.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Dyrk1b Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Dyrk1b
Function Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
Cellular Location Nucleus.
Tissue Location Isoform 1 and isoform 2 are broadly expressed. Isoform 3 seems specific for skeletal muscle (at protein level)
Research Areas
Citations (0)

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Dual-specificity kinase which possesses both serine/ threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments.


Janumyan, Y., et al. J. Biol. Chem. 283(49):34108-34120(2008)
Munton, R.P., et al. Mol. Cell Proteomics 6(2):283-293(2007)
Mercer, S.E., et al. J. Biol. Chem. 280(27):25788-25801(2005)
Collins, M.O., et al. J. Biol. Chem. 280(7):5972-5982(2005)
Deng, X., et al. J. Biol. Chem. 280(6):4894-4905(2005)

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$ 295.00
$ 99.00
Cat# AP14617c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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