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>   home   >   Products   >   Primary Antibodies   >   OVOL1 Antibody (N-term)   

OVOL1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - OVOL1 Antibody (N-term) AP14637a
    OVOL1 Antibody (N-term) (Cat. #AP14637a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the OVOL1 antibody detected the OVOL1 protein (arrow).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O14753
Other Accession Q9WTJ2, A2VDT4, NP_004552.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Antigen Region 1-29 aa
Additional Information
Other Names Putative transcription factor Ovo-like 1, hOvo1, OVOL1
Target/Specificity This OVOL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human OVOL1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOVOL1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OVOL1
Function Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the differentiation and/or maintenance of the urogenital system (By similarity).
Cellular Location Nucleus.
Tissue Location Expressed in fetal kidney, and also in adult pancreas and placenta. Not expressed in intestine, peripheral blood lymphocytes and ovary EMBL; BX648725; CAH56127.1; -; mRNA EMBL; BC059408; AAH59408.1; -; mRNA EMBL; AF016045; AAB72084.1; -; mRNA CCDS; CCDS8112.1; - RefSeq; NP_004552.2; NM_004561.3 UniGene; Hs.134434; - ProteinModelPortal; O14753; - SMR; O14753; - BioGrid; 111057; 5 IntAct; O14753; 3 STRING; 9606.ENSP00000337862; - iPTMnet; O14753; - PhosphoSitePlus; O14753; - BioMuta; OVOL1; - EPD; O14753; - MaxQB; O14753; - PaxDb; O14753; - PeptideAtlas; O14753; - PRIDE; O14753; - ProteomicsDB; 48206; - DNASU; 5017; - Ensembl; ENST00000335987; ENSP00000337862; ENSG00000172818 GeneID; 5017; - KEGG; hsa:5017; - UCSC; uc001ofp.4; human CTD; 5017; - DisGeNET; 5017; - EuPathDB; HostDB:ENSG00000172818.9; - GeneCards; OVOL1; - HGNC; HGNC:8525; OVOL1 HPA; HPA003984; - MIM; 602313; gene neXtProt; NX_O14753; - OpenTargets; ENSG00000172818; - PharmGKB; PA32853; - eggNOG; KOG3576; Eukaryota eggNOG; ENOG4111H28; LUCA GeneTree; ENSGT00920000149010; - HOGENOM; HOG000231694; - HOVERGEN; HBG053384; - InParanoid; O14753; - KO; K09216; - OMA; QPYQEPE; - OrthoDB; EOG091G0LB1; - PhylomeDB; O14753; - TreeFam; TF337552; - GenomeRNAi; 5017; - PRO; PR:O14753; - Proteomes; UP000005640; Chromosome 11 Bgee; ENSG00000172818; - CleanEx; HS_OVOL1; - ExpressionAtlas; O14753; baseline and differential Genevisible; O14753; HS GO; GO:0005634; C:nucleus; IBA:GO_Central GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0000981; F:RNA polymerase II transcription factor activity, sequence-specific DNA binding; ISA:NTNU_SB GO; GO:0001078; F:transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding; IEA:Ensembl GO; GO:0008544; P:epidermis development; IEA:Ensembl GO; GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IEA:Ensembl GO; GO:0001822; P:kidney development; IEA:Ensembl GO; GO:0007498; P:mesoderm development; IEA:Ensembl GO; GO:1901994; P:negative regulation of meiotic cell cycle phase transition; IEA:Ensembl GO; GO:2000647; P:negative regulation of stem cell proliferation; IEA:Ensembl GO; GO:0043588; P:skin development; IEA:Ensembl GO; GO:0007283; P:spermatogenesis; IEA:Ensembl GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW InterPro; IPR027756; Ovo-like InterPro; IPR036236; Znf_C2H2_sf InterPro; IPR013087; Znf_C2H2_type PANTHER; PTHR10032; PTHR10032; 1 SMART; SM00355; ZnF_C2H2; 4 SUPFAM; SSF57667; SSF57667; 2 PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3 PROSITE; PS50157; ZINC_FINGER_C2H2_2; 4 2: Evidence at transcript level; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger CHAIN 1 267 Putative transcription factor Ovo-like 1 /FTId=PRO_0000047011 ZN_FING 118 140 C2H2-type 1. {ECO:0000255|PROSITE- ProRule:PRU00042} ZN_FING 146 168 C2H2-type 2. {ECO:0000255|PROSITE- ProRule:PRU00042} ZN_FING 174 197 C2H2-type 3. {ECO:0000255|PROSITE- ProRule:PRU00042} ZN_FING 213 235 C2H2-type 4. {ECO:0000255|PROSITE- ProRule:PRU00042} CONFLICT 150 150 Y -> G (in Ref. 3; AAB72084) SEQUENCE 267 AA; 30259 MW; 57C67CD8A060A9B8 CRC64; MPRAFLVKKP CVSTCKRNWS ELPDEERGEI YVPVSLGFCP PQPYREPEPS VAEPPSCPLA LNMSLRDSSY SMAPGPCVVA QLPSEDMGHL TDPQSRDHGF LRTKMKVTLG DSPSGDLFTC RVCQKAFTYQ RMLNRHMKCH NDVKRHLCTY CGKGFNDTFD LKRHVRTHTG VRPYKCSLCD KAFTQRCSLE SHLKKIHGVQ QKYAYKERRA KLYVCEECGC TSESQEGHVL HLKEHHPDSP LLRKTSKKVA VALQNTVTSL LQGSPHL
Citations (0)

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Background

This gene encodes a protein highly similar to Drosophila and mouse proteins. In Drosophila the ovo protein plays a critical role in Drosophila oogenesis and cuticle formation. In mice the ovo like protein is involved in hair formation and spermatogenesis. The function of the human gene product has not been determined.

References

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Dai, X., et al. Genes Dev. 12(21):3452-3463(1998)
Chidambaram, A., et al. Mamm. Genome 8(12):950-951(1997)

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$ 295.00
$ 99.00
Cat# AP14637a
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(40 western blots)
Availability: In Stock
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