|Application ||WB, E|
|Other Accession||Q62764, Q9JKB3, NP_001138898.1, NP_003642.3|
|Calculated MW||40090 Da|
|Antigen Region||152-181 aa|
|Other Names||Y-box-binding protein 3, Cold shock domain-containing protein A, DNA-binding protein A, Single-strand DNA-binding protein NF-GMB, YBX3, CSDA, DBPA|
|Target/Specificity||This CSDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-181 amino acids from the Central region of human CSDA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CSDA Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||Highly expressed in skeletal muscle and heart.|
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Provided below are standard protocols that you may find useful for product applications.
CSDA binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity).
Lima, W.R., et al. J. Am. Soc. Nephrol. 21(3):478-488(2010)
Wang, G.R., et al. Acta Pharmacol. Sin. 30(10):1436-1442(2009)
Sharpe Elles, L.M., et al. Nucleic Acids Res. 37(19):6503-6514(2009)
Buchert, M., et al. Gastroenterology 137(1):156-164(2009)
Hayashi, J., et al. Int. J. Oncol. 21(4):847-850(2002)
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