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MSX2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MSX2 Antibody (Center) AP14677c
    MSX2 Antibody (Center) (Cat. #AP14677c) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MSX2 antibody detected the MSX2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35548
Other Accession Q03356, P70354, P52953, Q03358, P28362, Q0P5C3, P13297, P28360, P28361, O02786, P35993, P50223, NP_002440.2
Reactivity Human
Predicted Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 28897 Da
Antigen Region 120-148 aa
Additional Information
Gene ID 4488
Other Names Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8
Target/Specificity This MSX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human MSX2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMSX2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSX2
Synonyms HOX8
Function Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
Cellular Location Nucleus.
Research Areas
Citations (0)

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This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.


Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)
Satoh, K., et al. J. Gastroenterol. 45(7):763-770(2010)
Doi, T., et al. J. Pediatr. Surg. 45(6):1187-1191(2010)
Jagomagi, T., et al. Eur. J. Oral Sci. 118(3):213-220(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

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$ 295.00
$ 99.00
Cat# AP14677c
(40 western blots)
Availability: In Stock
Bulk Size
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