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Latexin Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP1467a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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Latexin Antibody (N-term) - Product info | |
| Application | WB, IHC
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| Primary Accession | Q9BS40 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 25750 Da |
Latexin Antibody (N-term) - Additional info | |
| Gene ID 56925 | |
| Other Names LXN; Latexin; Endogenous carboxypeptidase inhibitor; Protein MUM; Tissue carboxypeptidase inhibitor | |
| Target/Specificity This Latexin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31~60 amino acids from the N-terminal region of human latexin. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Latexin Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Latexin Antibody (N-term) - Protein Information | |
| Name LXN | |
| Function Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation | |
| Cellular Location Cytoplasm (Probable). | |
| Tissue Location Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain | |
Latexin Antibody (N-term) - Related products
AM1879a: LXN antibody( Ascites)
AP1467a: Latexin Antibody (N-term)
AP1467c: Latexin Antibody (Center)
LY11589a: LXN Over-expression Lysate
BP1467a: Latexin Antibody (N-term) Blocking Peptide
Latexin Antibody (N-term) - Application data
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Western blot analysis of Latexin Antibody (N-term) (Cat.#AP1467a) in HL60 cell line lysates (35ug/lane). Latexin (arrow) was detected using the purified Pab (1:60 dilution).
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Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with Latexin antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Formalin-fixed and paraffin-embedded human Spleen tissue reacted with Latexin antibody (N-term)(Cat.#AP1467a), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Latexin Antibody (N-term) - Research Areas
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BACKGROUND
Latexin possesses nearly irreversible, non-competitive and potent inhibition of zinc-dependent metallocarboxypeptidases CPA1, CPA2, and CPA4. It is expressed in a neuronal subset in the cerebral cortex and cells in other neural and non-neural tissues of rat. Latexin plays a role in regional specification and/or morphogenesis of the forebrain.
REFERENCES
Pallares,I., Proc. Natl. Acad. Sci. U.S.A. 102 (11), 3978-3983 (2005)
