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ALDH3A2 Antibody (N-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP1468a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
ALDH3A2 Antibody (N-term) - Product info | |
| Application | WB, IHC
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| Primary Accession | P51648 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 54848 Da |
ALDH3A2 Antibody (N-term) - Additional info | |
| Gene ID 224 | |
| Other Names ALDH3A2; ALDH10; FALDH; Fatty aldehyde dehydrogenase; Aldehyde dehydrogenase 10; Aldehyde dehydrogenase family 3 member A2; Microsomal aldehyde dehydrogenase | |
| Target/Specificity This ALDH3A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human *ALDH3A2 Antibody (N-term). | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ALDH3A2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ALDH3A2 Antibody (N-term) - Protein Information | |
| Name ALDH3A2 | |
| Synonyms ALDH10, FALDH | |
| Function Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid | |
| Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side | |
ALDH3A2 Antibody (N-term) - Related products
AM1840a: ALDH3A2 Antibody (Ascites)
AP1468a: ALDH3A2 Antibody (N-term)
AP1468b: ALDH3A2 Antibody (C-term)
RI10232: ALDH3A2 predesign siRNA
ALDH3A2 Antibody (N-term) - Application data
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Western blot analysis of anti-ALDH3A2 Antibody (N-term) Pab (Cat.#AP1468a) in mouse heart tissue lysates (35ug/lane). ALDH3A2 (arrow) was detected using the purified Pab (1:60 dilution).
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Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH3A2 antibody (N-term)(Cat.#AP1468a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
ALDH3A2 Antibody (N-term) - Research Areas
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BACKGROUND
Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. ALDH3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome.
REFERENCES
Chang, C., et al., Genomics 40(1):80-85 (1997). Rogers, G.R., et al., Genomics 39(2):127-135 (1997). De Laurenzi, V., et al., Nat. Genet. 12(1):52-57 (1996). Rogers, G.R., et al., Am. J. Hum. Genet. 57(5):1123-1129 (1995). Pigg, M., et al., Nat. Genet. 8(4):361-364 (1994).
