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ALDH6A1 AntibodyPeptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP1469d | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP1469d-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ALDH6A1 Antibody - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | Q02252 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 57840 Da |
ALDH6A1 Antibody - Additional info | |
| Gene ID 4329 | |
| Other Names ALDH6A1; MMSDH; Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Aldehyde dehydrogenase family 6 member A1 | |
| Target/Specificity This ALDH6A1 antibody is generated from rabbits immunized with human ALDH6A1 recombinant protein. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ALDH6A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
ALDH6A1 Antibody - Protein Information | |
| Name ALDH6A1 | |
| Synonyms MMSDH | |
| Function Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA | |
| Cellular Location Mitochondrion. | |
ALDH6A1 Antibody - Related products
AM1838a: ALDH6A1 Antibody (Ascites)
AP1469a: ALDH6A1 Antibody (N-term)
AP1469b: ALDH6A1 Antibody (C-term)
RI10237: ALDH6A1 predesign siRNA
DC01554: Human ALDH6A1 cDNA Clone
LY11652a: ALDH6A1 Over-expression Lysate
ALDH6A1 Antibody - Application data
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Western blot analysis of ALDH6A1 Antibody (Cat. #AP1469d) in HepG2 cell line lysates (35ug/lane). ALDH6A1 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded mouse brain tissue reacted with ALDH6A1 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ALDH6A1 Antibody (Cat. #AP1469d) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ALDH6A1 Antibody - Research Areas
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BACKGROUND
ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.
REFERENCES
Kuiper,H., Cytogenet. Genome Res. 109 (4), 533 (2005) Anderson,N.L., Mol. Cell Proteomics 3 (4), 311-326 (2004) Chambliss,K.L., J. Inherit. Metab. Dis. 23 (5), 497-504 (2000) Kedishvili,N.Y., J. Biol. Chem. 267 (27), 19724-19729 (1992)
