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> home > Products > Antibodies > Biological Process > Protein Amino Acid Phosphorylation > Mouse Ephb4 Antibody (Center)
Mouse Ephb4 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP14714c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP14714c-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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Mouse Ephb4 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | P54761 |
| Reactivity | Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 108848 Da |
Mouse Ephb4 Antibody (Center) - Additional info | |
| Gene ID 13846 | |
| Other Names Ephb4; Htk; Mdk2; Myk1; Ephrin type-B receptor 4; Developmental kinase 2; Hepatoma transmembrane kinase; Tyrosine kinase MYK-1 | |
| Target/Specificity This Mouse Ephb4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-389 amino acids from the Central region of Mouse Ephb4. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions Mouse Ephb4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
Mouse Ephb4 Antibody (Center) - Protein Information | |
| Name Ephb4 | |
| Synonyms Htk, Mdk2, Myk1 | |
| Function Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4- mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis | |
| Cellular Location Cell membrane; Single-pass type I membrane protein (By similarity) | |
| Tissue Location Expressed in various organ systems, including lung, liver, kidney, intestine, muscle and heart | |
Mouse Ephb4 Antibody (Center) - Related products
Mouse Ephb4 Antibody (Center) - Application data
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Mouse Ephb4 Antibody (Center) (Cat. #AP14714c) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ephb4 antibody detected the Ephb4 protein (arrow).
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Western blot analysis of Ephb4 (arrow) using rabbit polyclonal Mouse Ephb4 Antibody (Center) (Cat. #AP14714c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Ephb4 gene.
Mouse Ephb4 Antibody (Center) - Research Areas
AntibodiesBiological ProcessProtein Amino Acid PhosphorylationPost-translational Protein ModificationPhosphate Metabolic ProcessPhosphorus Metabolic ProcessPhosphorylationProtein Modification ProcessBiopolymer ModificationMetabolic ProcessPrimary Metabolic ProcessProtein Metabolic ProcessCellular Protein Metabolic ProcessCellular Metabolic ProcessCellular ProcessMacromolecule Metabolic ProcessEnzyme Linked Receptor Protein Signaling PathwayCellular Macromolecule Metabolic ProcessTransmembrane Receptor Protein Tyrosine Kinase Signaling PathwayCellular CompartmentIntegral To Plasma MembraneIntrinsic To Plasma MembranePlasma Membrane Part
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Receptor for members of the ephrin-B family. Binds to ephrin-B2.
