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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   C4orf49 Antibody (C-term)   

C4orf49 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - C4orf49 Antibody (C-term) AP14729b
    C4orf49 Antibody (C-term) (Cat. #AP14729b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the C4orf49 antibody detected the C4orf49 protein (arrow).
  • IHC-P - C4orf49 Antibody (C-term) AP14729b
    C4orf49 Antibody (C-term) (AP14729b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of C4orf49 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TDB4
Other Accession NP_116012.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 25390 Da
Antigen Region 176-204 aa
Additional Information
Gene ID 84709
Other Names Protein MGARP, Corneal endothelium-specific protein 1, CESP-1, Hypoxia up-regulated mitochondrial movement regulator protein, Mitochondria-localized glutamic acid-rich protein, Ovary-specific acidic protein, MGARP, C4orf49, CESP1, HUMMR, OSAP
Target/Specificity This C4orf49 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the C-terminal region of human C4orf49.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC4orf49 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C4orf49, CESP1, HUMMR, OSAP
Function Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia. Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity).
Cellular Location Membrane; Single-pass membrane protein. Mitochondrion. Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion.
Tissue Location Expressed in the brain, adrenal gland and corneal endothelium (CE). Expressed in steroid-producing cells of the ovary and testis (at protein level). Expressed in steroid- producing cells of the ovary and testis. Weakly expressed in placenta. Expressed in corneal endothelial cells
Research Areas
Citations (0)

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The function of this protein remains unknown.


Matsumoto, T., et al. Endocrinology 150(7):3353-3359(2009)
Li, Y., et al. J. Cell Biol. 185(6):1065-1081(2009)
Kinouchi, R., et al. Invest. Ophthalmol. Vis. Sci. 47(4):1397-1403(2006)
Sakai, R., et al. Invest. Ophthalmol. Vis. Sci. 43(6):1749-1756(2002)

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Cat# AP14729b
(40 western blots)
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