- Antibodies
- New
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Tag
- Peptides
- Biological Process >
- Cellular Compartment >
- Disease >
- Molecular Function >
- Pathway Biocarta >
- Pathway KEGG >
- Pathway Panther >
- Tissue >
- Amino Acids
- Tag
- Biological Process >
- Proteins
- RNAi
- FL cDNA Clones
- Cell/Tissues/Lysates
ALDH5A1 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
Australia Austria Belgium Brazil Bulgaria Canada China Croatia Cyprus Czech Republic Denmark Estonia Finland France Germany Greece Hungary Iceland India Indonesia Ireland Israel Italy Japan Korea Latvia Lithuania Luxembourg Macedonia Malaysia Malta Netherlands Norway Pakistan Poland Portugal Romania Serbia Singapore Slovakia Slovenia Spain Sweden Switzerland Taiwan Turkey United Kingdom United States Vietnam Others 
|
|||
|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP1472a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
ALDH5A1 Antibody (N-term) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | P51649 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 57215 Da |
ALDH5A1 Antibody (N-term) - Additional info | |
| Gene ID 7915 | |
| Other Names ALDH5A1; SSADH; Succinate-semialdehyde dehydrogenase, mitochondrial; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase | |
| Target/Specificity This ALDH5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135~165 amino acids from the N-terminal region of human ALDH5A1. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:10~50 FC~~1:10~50 | |
| Format Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ALDH5A1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ALDH5A1 Antibody (N-term) - Protein Information | |
| Name ALDH5A1 | |
| Synonyms SSADH | |
| Function Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) | |
| Cellular Location Mitochondrion. | |
| Tissue Location Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta | |
ALDH5A1 Antibody (N-term) - Related products
AM1839a: ALDH5A1 Antibody (Ascites)
AP1472a: ALDH5A1 Antibody (N-term)
AP1472b: ALDH5A1 Antibody (C-term)
RI10236: ALDH5A1 predesign siRNA
ALDH5A1 Antibody (N-term) - Application data
-
Western blot analysis of ALDH5A1 (arrow) using rabbit polyclonal ALDH5A1 Antibody (N-term) (Cat. #AP1472a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH5A1 gene (Lane 2) (Origene Technologies).
-
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH5A1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
-
Flow cytometric analysis of ATDC5 cells using ALDH5A1 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ALDH5A1 Antibody (N-term) - Research Areas
Abgent welcomes feedback from its customers.
If you have used an Abgent product and would like to share how it has performed, please click on the
"Submit Review" button and provide the requested information. Our staff will examine and post your
review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abgent.com.
Thank you for your support.
Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.
REFERENCES
Knerr,I., J. Inherit. Metab. Dis. 30 (3), 279-294 (2007) Blasi,P., J. Mol. Evol. 63 (1), 54-68 (2006) Plomin,R., Mol. Psychiatry 9 (6), 582-586 (2004)
