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ALDH5A1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ALDH5A1 Antibody (N-term) AP1472a
    Anti-ALDH5A1 Antibody (N-term) at 1:1000 dilution + human liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - ALDH5A1 Antibody (N-term) AP1472a
    Western blot analysis of ALDH5A1 (arrow) using rabbit polyclonal ALDH5A1 Antibody (N-term) (Cat. #AP1472a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ALDH5A1 gene (Lane 2) (Origene Technologies).
  • IHC-P - ALDH5A1 Antibody (N-term) AP1472a
    Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH5A1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - ALDH5A1 Antibody (N-term) AP1472a
    Flow cytometric analysis of ATDC5 cells using ALDH5A1 Antibody (N-term) (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51649
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57215 Da
Antigen Region 128-157 aa
Additional Information
Gene ID 7915
Other Names Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, ALDH5A1, SSADH
Target/Specificity This ALDH5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-157 amino acids from the N-terminal region of human ALDH5A1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALDH5A1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALDH5A1
Synonyms SSADH
Function Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Cellular Location Mitochondrion.
Tissue Location Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta
Research Areas
Citations (0)

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ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.


Knerr,I., J. Inherit. Metab. Dis. 30 (3), 279-294 (2007) Blasi,P., J. Mol. Evol. 63 (1), 54-68 (2006) Plomin,R., Mol. Psychiatry 9 (6), 582-586 (2004)

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$ 295.00
$ 99.00
Cat# AP1472a
(40 western blots)
Availability: In Stock
Bulk Size
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