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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CD70 Antibody (Center)   

CD70 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CD70 Antibody (Center) AP14744c
    CD70 Antibody (Center) (Cat. #AP14744c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the CD70 antibody detected the CD70 protein (arrow).
  • IHC-P - CD70 Antibody (Center) AP14744c
    CD70 Antibody (Center) (AP14744c)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CD70 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32970
Other Accession NP_001243.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21118 Da
Antigen Region 72-101 aa
Additional Information
Gene ID 970
Other Names CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7
Target/Specificity This CD70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the Central region of human CD70.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD70 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD70
Synonyms CD27L, CD27LG, TNFSF7
Function Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Cellular Location Membrane; Single-pass type II membrane protein
Research Areas
Citations (0)

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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.


Arimoto-Miyamoto, K., et al. Immunology 130(1):137-149(2010)
Shaw, J., et al. Blood 115(15):3051-3057(2010)
Yu, S.E., et al. Mol. Cells 29(2):217-221(2010)
Kozlowska, A., et al. J. Rheumatol. 37(1):53-59(2010)
Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) :

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$ 295.00
$ 99.00
Cat# AP14744c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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