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COIL Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - COIL Antibody (Center) AP14748c
    COIL Antibody (Center) (Cat. #AP14748c) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the COIL antibody detected the COIL protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P38432
Other Accession NP_004636.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 62608 Da
Antigen Region 157-186 aa
Additional Information
Gene ID 8161
Other Names Coilin, p80-coilin, COIL, CLN80
Target/Specificity This COIL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-186 amino acids from the Central region of human COIL.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCOIL Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CLN80
Function Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.
Cellular Location Nucleus. Nucleus, Cajal body
Tissue Location Found in all the cell types examined.
Research Areas
Citations (0)

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The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.


Shanbhag, R., et al. FEBS Lett. 584(20):4351-4356(2010)
Tapia, O., et al. Chromosoma 119(5):527-540(2010)
Toyota, C.G., et al. Chromosoma 119(2):205-215(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Hearst, S.M., et al. J. Cell. Sci. 122 (PT 11), 1872-1881 (2009) :

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$ 295.00
$ 99.00
Cat# AP14748c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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