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DNAJA3 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DNAJA3 Antibody (N-term) AP14750a
    DNAJA3 Antibody (N-term) (Cat. #AP14750a) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the DNAJA3 antibody detected the DNAJA3 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96EY1
Other Accession Q99M87, NP_001128582.1, NP_005138.3
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 52489 Da
Antigen Region 105-134 aa
Additional Information
Gene ID 9093
Other Names DnaJ homolog subfamily A member 3, mitochondrial, DnaJ protein Tid-1, hTid-1, Hepatocellular carcinoma-associated antigen 57, Tumorous imaginal discs protein Tid56 homolog, DNAJA3, HCA57, TID1
Target/Specificity This DNAJA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-134 amino acids from the N-terminal region of human DNAJA3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDNAJA3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HCA57, TID1
Function Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma- mediated transcriptional activity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway.
Cellular Location Mitochondrion matrix. Cytoplasm, cytosol. Cell junction, synapse, postsynaptic cell membrane; Peripheral membrane protein Note=Recruited to the postsynaptic cell membrane of the neuromuscular junction through interaction with MUSK
Tissue Location Widely expressed with highest levels in heart, liver, lung and skeletal muscles. Also expressed in keratinocytes
Research Areas
Citations (0)

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DNAJA3 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins. For background information on the DNAJ family, see MIM 608375.


Qian, J., et al. Gastroenterology 138(4):1418-1428(2010)
Kurzik-Dumke, U., et al. J Transl Med 8, 58 (2010) :
Linnoila, J., et al. Neuron 60(4):625-641(2008)
Kurzik-Dumke, U., et al. Int. J. Mol. Med. 21(1):19-31(2008)
Kurzik-Dumke, U., et al. Cell. Signal. 19(9):1973-1985(2007)

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Cat# AP14750a
(40 western blots)
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